BCL2 and cancer: Ongoing clinical trials with ASOs targeting Bcl-2 (NCT04072458), Grb2 (NCT04196257), and androgen receptor (AR; NCT03300505) as well as future mRNA (Laikova et al., 2019) and non-coding RNA targets (Slack and Chinnaiyan, 2019) for the treatment of various solid tumors will in time tell of the efficacy of ASOs for cancer treatment.