We analyzed 29 elderly CN-AML samples with DNA methylation data and RNA sequencing from TCGA database and identified 41 up-regulated and 33 down-regulated lncRNAs which were significantly related with AQP1 methylation (P < 0.05), the heat map and volcano plot for different lncRNAs were shown in Figure S13. The gene discussed is AQP1; the disease is acute myeloid leukemia.