ERBB2 and neoplasm: Figure 2 shows two representative cases, one with positive HER2 status and one with negative HER2 status. The detailed characteristics of the 76 cases are presented in Table 2. There was no significant association between HER2 2+ status and patient characteristics. A randomly selected case (HER2 status, positive) is shown in Figure 3 to illustrate the results of tumor segmentation and intratumoral regionalizaton based on the method proposed above.