Survivin phosphorylation on Thr34 is regulated by CDK1/P34cdc2 cyclin B1 supported by human cervical adenocarcinoma, oral sub-mucosal fibrosis and oral squamous cell carcinoma studies.16 Unlike other IAP family members, survivin has only one BIR domain. Here, BIRC5 is linked to oral cavity squamous cell carcinoma.