We validated the effects of PEX5 and miR-31-5p on HCC radiosensitivity in vivo by using a miR-31-5p agomir to elevate miR-31-5p expression levels (Figure 6A) and found that the growth of tumors treated with the combination of PEX5 knockdown and radiation was slower than that of tumors treated with radiation or PEX5 knockdown alone. The gene discussed is PEX5; the disease is hepatocellular carcinoma.