Meanwhile, Tóth et al. (2014) reported that methylated SEPT9 could be detected in 100% (26/26) of adenomas and 97.1% (33/34) of CRC tissues, but methylated SEPT9 was positive in only 30.8% (8/26) of adenomas and 88.2% (30/34) of CRC in plasma (), indicating a higher level of SEPT9 methylation in tissues than that in plasma. Here, SEPTIN9 is linked to colorectal carcinoma.