TNF and tuberculosis: Functional categories (GO) and pathways (KEGG) associated with Mtb infection in AMCTs and AMTBs, responding to a robust inflammatory response to lipopolysaccharide, the TNF signaling pathway, cytokines and chemokines, activation of toll-like receptors (TLRs) and the NF-kappa B signaling pathway, and TB, are relevant (Figure 2A).