GJB2 and infection: In contrast, seven genes (5%) were differentially expressed in response to infection with clinical isolate, UT127 (Figure 1B, Supplementary Table 2), of which five genes were upregulated, including FAM129A, GJB2, and ZSWIM4, and signaling receptors, such as ADORA2A, and prostaglandin E receptor 4 (PTGER4), were significantly enriched in a single functional category, such as negative regulation of inflammatory response (p = 5.75 × 10−4).