An obvious reduction was observed after treatment with myricetin in the serum levels of PC III (84.72 ± 12.32 ng/mL), collagen IV (51.55 ± 12.14 ng/mL), laminin (62.02 ± 17.79 ng/mL) and hyaluronidase (158 ± 16.92 ng/mL) compared to the infected mice [PC III: F(3, 20) = 164.3, P < 0.001; collagen IV: F(3, 20) = 164.4, P < 0.001; laminin: F(3, 8) = 28, P = 0.125and hyaluronidase: F(3, 20) = 158.9, P < 0.001, respectively], suggesting that myricetin has an inhibitory effect on liver fibrosis caused by S. japonicum infection (Figure 4). The gene discussed is LAMB2; the disease is Hepatic fibrosis.