Analysis of brain CCL2 concentrations revealed no significant interaction between sex and bacterial infection at 24 h or 5 days after infection, but there was a significant effect of bacterial infection on brain CCL2 levels at 24 h [F(1, 17) = 36.84, p < 0.0001] and 5 d [F(1, 19) = 7.20, p = 0.01]. Here, CCL2 is linked to bacterial infectious disease.