MKI67 and neoplasm: As expected, PFS was also significantly associated with ENSAT tumor stage (stage 1–2 vs. 3–4, p = 0.001, HR = 2.25, 95% CI = 1.39–3.64), Ki67 proliferation index (cut-off 15%, p < 0.001, HR = 3.53, 95% CI = 2.11–5.89), and resection status (R0-X vs. R1–2, p < 0.001, HR = 6.49, 95% CI 2.5–16.8).