Males with hypogonadism tended to be older (mean ± SD: 35.2 ± 10.9 years vs. 29.4 ± 10.4 years; p = 0.054), having a lower level of testosterone (mean ± SD: 9.3 ± 5.0 nmol/L vs. 15.6 ± 4.7 nmol/L; p < 0.001) as well as higher values of LH (mean ± SD: 11.2 ± 6.6 mIU/mL vs. 5.9 ± 1.4 mIU/mL; p = 0.001), FSH (mean ± SD: 24.2 ± 10.4 IU/L vs. 9.8 ± 3.5 IU/L; p < 0.001) and FSH/LH ratio (mean ± SD: 2.3 ± 0.6 vs. 1.7 ± 0.7; p < 0.01) (Figure 3D) than males without hypogonadism. The gene discussed is PLOD1; the disease is hypogonadism.