Moreover, HGF in circulation is positively correlated with the mass of perivascular fat, waist circumference, body mass index, body fat content and the development of insulin resistance (Vistoropsky et al., 2009; Rittig et al., 2012; Courten et al., 2013; Tsukagawa et al., 2013; Bancks et al., 2016). The gene discussed is HGF; the disease is Insulin resistance.