AKT1 and neoplasm: However, due to the sparse knowledge about their connection to chromanols and chromenols, further topics, like the interaction of tumor and immune cells, adhesion proteins, structure and regulation of tumor microenvironments, mechanisms for programed cell death as well as other prominent signaling pathways (PI3K/Akt/mTOR; PKC; STAT; Wnt/β-catenin), were not considered in this review.