NTRK2 and attention deficit-hyperactivity disorder: To date, these behavioral alterations have been mainly related to a dysfunctional striatal dopamine turnover due to the total or partial DAT gene silencing and to alterations in frontostriatal BDNF, trkB and post-synaptic density protein 95 (PSD-95) levels, leading to consider these animals as a new model for the study of pathological hyperdopaminergic conditions ranging from the attention-deficit/hyperactivity disorder (ADHD) to autism and psychosis spectrum disorders (Leo et al., 2018a).