Glucose-6-phosphate dehydrogenase deficiency is an inherited X-linked enzymopathy present in up to 20% of malaria-endemic populations.9 Males have a single copy of the gene and are either hemizygous G6PD deficient with < 30% of normal G6PD activity or normal.10 By contrast, females have two copies of the gene and can be homozygous G6PD normal or deficient, or heterozygous. This evidence concerns the gene G6PD and malaria.