We examined 35 NSCLC cases, of which 23 had known rearrangements confirmed by fluorescence in situ hybridization (FISH) and immunohistochemistry; 11 cases were ROS1 rearranged, eight ALK rearranged, and four were RET rearranged NSCLC (Table 2). The gene discussed is ALK; the disease is non-small cell lung carcinoma.