According to the ROC analysis, the plasma PTX3 level at OPU2 was not better than CRP for predicting early OHSS: the AUCs of the best cut-offs for PTX3 were 0.79 (P = 0.007) and for CRP 0.87 (P < 0.001) (Fig. 2). The gene discussed is CRP; the disease is ovarian hyperstimulation syndrome.