SVEP1 and hepatocellular carcinoma: All these results suggest that the decrease in SVEP1 expression induces the metastasis and proliferation of HCC cells, which corroborates our previous clinical data analysis showing that patients with HCCs with low-SVEP1 expression levels have an increased likelihood of having increased tumors sizes and microsatellite nodules (Fig. 2f and g, Table S4).