Chen et al. previously reported lower serum Tetranectin levels in patients with coronary artery disease (proportional to the disease burden) compared to healthy subjects and hypothesized that atherosclerosis-related endothelial damage might lead to intimal accumulation of Tetranectin in atherosclerotic plaque complexes with Lipoprotein (a) and/or fibrin, thus diminishing serum Tetranectin levels25. Here, CLEC3B is linked to coronary artery disorder.