Except for IL-6, all of these cytokines were specifically detected only in co-cultures of UniCAR T-cells with STn+ cancer cells in the presence of αSTn or αSTn-IgG4 TMs, with a significantly higher amount of secreted cytokines for the αSTn-IgG4 TM in comparison to the αSTn TM. The gene discussed is IL6; the disease is cancer.