In support of our findings, previous oncolytic NDV findings generated from glioblastoma multiforme tumor in xenotransplant murine models have shown that virotherapy with NDV leads to enhanced infiltration of IFN-gamma+ CD4+/CD8+ T cells along with a decrease in myeloid-derived suppressor cells (MDSCs) in the tumor microenvironment [36]. This evidence concerns the gene CD4 and neoplasm.