Notably, several of the genes among those with large variation in differential expression between the two cell lines included the adhesion molecule ICAM-1 and molecules important for chemotaxis, such as CXCR4 and CSF1, which are highly expressed in MCL cells [38], as well as CCL4, which is known to increase upon BCR engagement [39]. Here, CXCR4 is linked to mantle cell lymphoma.