Several reports suggest the overexpression of JMJD10/MINA53 in multiple cancers such as colorectal, lung, esophageal, glioblastoma, lymphoma, cholangiocarcinoma, gingival squamous cell carcinoma, neuroblastoma, liver, pancreatic, multiple myeloma, breast, and gastric cancer [5,10,18,19,20,21,22,23,24,25,26]. The gene discussed is RIOX2; the disease is AL amyloidosis.