When compared with the normal endometrium, SNAI1 was upregulated as early as in the noninvasive (stage 1A) and myoinvasive (stage 1B) tumors, followed by the expression of TWIST1, ZEB1, and SNAI2 in the myoinvasive (stage 1C) tumors of endometrioid endometrial carcinoma [43]. This evidence concerns the gene SNAI2 and endometrial endometrioid carcinoma.