Once controls were removed from the correlation study, BAMBI transcript levels positively correlated with PrPSc deposition in scrapie animals (r = 0.98, p = 0.003) and spongiosis scores showed significant positive correlation with the expression levels of GALT (r = 0.962, p = 0.009), PAPSS2 (r = 0.968, p = 0.007) and RGS4 (r = 0.938, p = 0.018). The gene discussed is RGS4; the disease is scrapie.