The described upregulated expression of DNMTs in the endometriotic tissue, which leads to hypermethylation (the gene that will be silenced is methylated), has been clearly observed in eutopic endometrium in infertile women with endometriosis only for the DNMT3A transcript and not for DNMT1 and DNMT3B [106]. This evidence concerns the gene DNMT3B and endometriosis.