DNMT3B and endometriosis: Conversely, for hypomethylation (the gene that will not be silenced is not methylated), lower expression of DNMT1 has been demonstrated in eutopic and ectopic endometria of endometriosis patients compared with that in control endometria, and the level of DNMT3B was significantly lower in ectopic endometria compared with eutopic and control endometria [107,108].