WNT4 and endometriosis: GWAS studies in women with endometriosis revealed numerous genes, including the genes associated with uterine development and stem cell function (WNT4), ovulatory function (ESR1, FSHB), and those regulating the activity of estrogen and estradiol biosynthesis (ESR1, GREB1, SYNE1, CYP2C19, CCDC170); most of these genes are also associated with ovarian cancer [68,69,70].