TNF and nervous system disorder: Thus, an incorrect control of neuroinflammation, such as when it is prolonged over time, making it too aggressive and producing too many proinflammatory factors such as interleukin 6 (IL-6), interleukin 1β (IL-1β), or tumor necrosis factor (TNFα), or when it appears for no apparent reason, as in autoimmune diseases, could contribute to the etiology of neurological disease [11].