In line with the above reports, it has recently been shown that the same CCK receptor antagonist blocks dietary fat-induced growth of pancreatic cancer cells, inhibits metastases in vivo as well as decreases tumor fibrosis; whereas CCK analogue is able to stimulate the growth of Panc02 cells in vitro as long as they possess a functional CCK receptor [192]. Here, CCK is linked to familial pancreatic carcinoma.