The main findings, following l-carnitine treatment, were prevention of cancer cell growth; inhibition of Histone Deacetylases HDAC I/II activities caused by l-carnitine binding to HDAC active sites; elevation of histone acetylation and acetylated lysine accumulation; and induction of p21cip1 gene, mRNA and protein expression in cancer cells [62]. Here, CDKN1A is linked to cancer.