MAPT and intrahepatic cholangiocarcinoma: A weekly investigation of the gene expression revealed a continuous progress in neuronal differentiation and increase in the level of maturation markers, such as the dendritic marker Microtubule-associated protein 2 (MAP2) or Microtubule-associated protein tau (MAPT), and RNA Binding Fox-1 Homolog 3 (RBFOX3, also known as NeuN) (Figure 3), which were in accordance with the protein data of immunofluorescent staining of the 3D spheroids, MAP2 and Neurofilament 200 kDa (NF200); (ICC, Figure 2A,B).