CCL16 and breast cancer: This chemokine was shown to delay mammary tumor growth and reduce rates of metastasis in mouse models [115], raising the possibility of decreased immune surveillance of our patient’s MPNST secondary to a non-functional CCL16. In addition to the differences in single nucleotide variants, there were differences in copy number alterations across the three areas with Area 2 showing the most distinct signature in terms of copy number gains and losses.