When combined with the previously-reported associations with IOP and glaucoma, our results provide compelling genetic evidence of the role of ANGPTL7 in glaucoma and its subtypes including exfoliation, primary open-angle, and primary angle-closure, which may come in contrast to prior findings with lack of overlap between POAG risk and IOP loci [32]. The gene discussed is ANGPTL7; the disease is open-angle glaucoma.