ANGPTL7 and glaucoma: For p.Gln175His in ANGPTL7, using logistic regression analysis with age, sex, and principal components (PC1-PC4) as covariates, we estimated that the variant lowers glaucoma risk by 34% (P = 0.00543; OR = 0.66 [95% CI: 0.366–0.954], Table 2).