In this sub-group, a stronger effect was observed (P = 1.3x10-8, OR = 0.68) versus those glaucoma cases without a definitive record of POAG (OR = 0.77 [95% CI: 0.67–0.88]), reminiscent of the stronger risk effects seen at the myocilin (MYOC) gene and other established genes in the POAG subgroup [17]. This evidence concerns the gene MYOC and glaucoma.