Confirmation of an ANGPTL7 effect on glaucoma risk was seen in data from an independent Finnish-specific protein-altering missense substitution, p.Arg220Cys, which was strongly associated with protection from glaucoma (P = 2.0x10-12, OR = 0.71 [95% CI: 0.64–0.78], S7 Fig). This evidence concerns the gene ANGPTL7 and glaucoma.