EGFR and neoplasm: For example, the AUC of Cetuximab and AZD3759, which both are epidermal growth factor receptor (EGFR) inhibitors,25, 26 were found to have the most significant positive correlation with progenitorness score in two versions of GDSCs separately, which suggest a resistance to EGFR inhibitors for tumours with high progenitorness scores.