We further constructed 144aa‐uORF(+), ZNRD1‐AS1(−), miR‐499a‐5p up‐regulation and knockdown, ZNRD1‐AS1 and miR‐499a‐5p cotransfection, and miR‐499a‐5p and ELF1 cotransfection into glioma cells. The gene discussed is PTGDR; the disease is central nervous system cancer.