METTL3 and hepatocellular carcinoma: To explore the mechanism by which METTL3 depletion activates autophagy in HCC, we performed an autophagy real‐time quantitative PCR array to profile gene expression in METTL3‐knockdown HCC cells and observed good consistent results between the two independent shRNAs of METTL3 in three HCC cell lines (Appendix Fig S4A).