METTL3 and hepatocellular carcinoma: Rescue with wild‐type METTL3 in METTL3‐knockdown HCC cells significantly restored the binding of FOXO3 mRNA to YTHDF1, while a rescue using mutant METTL3 only showed a slight increase in binding compared to the control (Appendix Fig S4I), suggesting that METTL3‐mediated m6A methylation at the 3′UTR of FOXO3 promoted FOXO3 mRNA stability in an YTHDF1‐dependent manner.