A total of 30 lncRNAs (7 protective lncRNAs, WRAP53, TRPM3, TCL6; SEMA3G, CCND1 and DAPK1; and 23 potentially risk lncRNAs, SNHG3, MIAT, HOTAIR, MINA, HAR1A, DISC2, SRA1, SNHG11, DMPK, PVT1; MIR155HG, KCNQ1OT1, DLEU2, HYMAI, PRINS, MEG3, RRP1B, SNHG4, MALAT1 GAS5, FADS1, HAR1B and PCGEM1; Figure S1 of Additional file 1) were validated to be significantly related to overall survival in the ccRCC patients. This evidence concerns the gene HOTAIR and nonpapillary renal cell carcinoma.