Moreover, IHC revealed thatPD-L1 expression in PTC+HT tumor tissues were slightly lower than their adjacent non-tumor tissues, and the levels of PD-L1 expression in PTC tumor tissues were significantly higher than that in their adjacent non-tumor tissues and the PTC+HT tumor tissues (P<0.001, Fig. 5F and 5G). The gene discussed is CD274; the disease is neoplasm.