Schaefer et al. 10 observed that ERG-positive status was associated with low-serum PSA and lower prostate volume, while Huang et al. 11 further confirmed the ERG-positive status was associated with Gleason score and higher biochemical relapse rate but not with presurgical PSA levels, tumor volume, pathological stage, surgical margin or lymphovascular invasion. This evidence concerns the gene ERG and neoplasm.