TRIM4 and neoplasm: Multivariate analysis revealed that TRIM4 expression (hazard ratio, 0.566; 95% CI, 0.345-0.930; p=0.025), tumour diameter (hazard ratio, 1.804; 95% CI, 1.131-2.876; p=0.013) and vascular invasion (hazard ratio, 1.802; 95% CI, 1.115-2.912; p=0.016) were independent predictive factors for RFS (Table 2).