PPARGC1A and obesity due to melanocortin 4 receptor deficiency: Therefore, in an attempt to realize the molecules involved in the pathogenesis of obesity, here, we aimed to evaluate the expression of MALAT1 and TUG1, as well as plausible target genes (PPARγ, PGC1α, SREBP-1c, FAS, and ACC), in VAT and SAT from obese women compared to normal-weight subjects.