The study revealed significantly low concentrations of Pg (ng/ml) mean in cows with abortion (2.45±1.509), dystocia (8.59±0.402), vaginal prolapse (4.67±0.301), downer cow syndrome (4.40±1.222), and retained placenta (3.78±0.151) (Table-4 and Figure-1). The gene discussed is JUP; the disease is abortion.