IL6 and lymphoproliferative syndrome: Nakabayashi et al. reported that tumor growth factor-β knockout mice showed multiple lymphoproliferative disorders similar to those observed in the pseudolymphoma of Sjögren’s syndrome, and that upregulation of several inflammatory cytokine genes, interferon-γ, interleukin (IL)-1, IL-6, and IL-10, was observed in their salivary glands [52].