Freshly isolated monocytes from patients with CF did not show any differences in the surface marker expression of CD68 and CD80, but significantly higher expression of CD163 and CD206 was observed when compared with HC monocytes [172]; however, the monocytes of two different patient cohorts, on Ivacaftor and Ivacaftor/Lumacaftor, showed normalisation of the increased levels of CD163 and CD206, which were comparable to the levels of HC monocytes [172]. Here, MRC1 is linked to cystic fibrosis.