Briefly, subjects with positive QFT and TST results and no clinical or radiological evidence of active TB were classified as LTBI, without considering the exposure period to Mtb. In the present work, we confirmed those previous findings showing that non TB QFT positive individuals produced significant higher levels of IFN-γ against Rv2626c than QFT negative subjects and TB patients (Fig. 3a). This evidence concerns the gene IFNG and tuberculosis.