Other miRs including miR-9, miR-21, miR-146, miR-147 and miR-187 are decreased in SS and attenuate inflammation by repressing positive regulators of inflammation including programmed cell death protein 4 (PDCD4), nuclear factor kappa-light-chain-enhancer of activated B cells (NFκB), interleukin-1 receptor-associated kinase 1 (IRAK1) and TNF receptor associated factor 6 (TRAF6)20,22. Here, IRAK1 is linked to synovial sarcoma.