We injected bEnd.3 (−) or CD274-bEnd.3 (+) cells into tumor tissues separately, and found that the tumor tissues with bEnd.3 (+) group (injected intratumorally CD274-bEnd.3 (+)) had a faster growth rate compared to the bEnd.3 (−) group (injected intratumorally bEnd.3 (−)) (Fig. 7a–c). Here, CD274 is linked to neoplasm.