Association with seminoma was found for mutations in KIT, KRAS and NRAS and for putative oncogenic driver genes CBL, RAC1, PIK3CA, and CTNNB1 (analysed jointly due to lower frequency), p = 3.33 × 10−10, p = 1.41 × 10−6, p = 0.002, p = 0.009, respectively. The gene discussed is RAC1; the disease is seminoma.