On the other hand, the addition of TKI including sorafenib or quizartinib to higher intensity chemotherapy was associated with 47% reduction in the risk of death in patients newly diagnosed with FLT3 mutant AML, taking in consideration that the majority of our patients received triplet combination of induction chemotherapy, unlike ‘doublets’ commonly used in induction regimens. Here, FLT3 is linked to acute myeloid leukemia.