NFKB1 and psoriasis: At the 2p15 locus, the psoriasis association tagged by rs10865331 was originally assigned to the nearest gene B3GNT2; however, the CHi-C interactions skipped B3GNT2 (~ 120 kb upstream) and instead implicated the promoter of copper metabolism domain containing 1 (COMMD1), a gene involved in NFkB signalling, over approximately 435 kb upstream (Fig. 2a) [30, 33].