Expressed genes interacting with GWAS fragments included compelling psoriasis candidates such as IL23A, PTGER4, STAT3 and NFKBIZ. Importantly, we found that other-end fragments of CHi-C interactions were significantly enriched for transcription start sites of expressed genes in the corresponding cell type (Additional file 3, Fig. S2). The gene discussed is PTGER4; the disease is psoriasis.