Lanreotide is a synthetic octapeptide analog of natural somatostatin with a longer half-life (t1⁄2) than the native molecule, and a selective somatostatin receptor subtype agonist with a high affinity for human somatostatin receptors 2 and 5 [5], which are commonly expressed at both the mRNA [6] and protein [7] level in GH-secreting pituitary tumors. This evidence concerns the gene GH1 and pituitary tumor.